Rancher installed istio performance report

Information
rancher:2.6.1
istio:1.10.4
k8s:1.21.14

Request
We are using rancher(2.6.1) to manage k8s cluster. Already installed istio(1.10.4). We are planning to use istio proxy supporting mtls in service mesh.

Do you have any good practise on istio ?
Also Can you give us some performance test report of running istio in rancher?